Around the time of the Third War, Greymane instructed Archmage Arugal, a Dalaran wizard loyal to Gilneas, to summon feral worgen to protect Gilneas from the Scourge threat. The plan backfired, and the worgen curse would eventually run rampant among the Gilnean population. In the time between the Third War and the War against the Lich King, the number of those afflicted with the Worgen curse had grown and were now attacking Gilneas City. To counter the threat, Greymane helped to defend the city and aided in the evacuation of citizens to Duskhaven. In the aftermath, Greymane faced the dual threats of the Cataclysm and the Forsaken invasion, culminating in the battle to retake Gilneas City from the Forsaken and witnessing the death of his son and heir, Liam.